WJOGとは

業績

2025年5月31日現在

Publication
year
WJOG
Trial No.
Trial
name
Cancer
group
TitleFirst
Author
Journalpubmed
2025WJOG18524GRAINBIRDGIWJOG18524G: a single-arm phase II study evaluating bemarituzumab combined with ramucirumab and paclitaxel in fibroblast growth factor receptor 2b (FGFR2b)-positive advanced gastric or gastroesophageal junction cancer (RAINBIRD)Keitaro ShimozakiESMO Gastrointest Oncolhttps://pubmed.ncbi.nlm.nih.gov/41647978/
2025WJOG16322GGIA multicenter Phase II study of mFOLFOX6 plus nivolumab for gastric cancer with severe peritoneal metastases: WJOG16322GMunehiro WakabayashiFuture Oncolhttps://pubmed.ncbi.nlm.nih.gov/40476844/
2025WJOG15721BRealisEBreastRisk factors for early recurrence in patients with hormone receptor-positive, HER2-negative breast cancer: a retrospective cohort study in Japan (WJOG15721B)Rurina WatanukiBreast Cancerhttps://pubmed.ncbi.nlm.nih.gov/40208504/
2025WJOG14320BERICABreastOlanzapine for nausea and vomiting in people with breast cancer treated with trastuzumab deruxtecan: plain language summary of the ERICA studyHitomi SakaiFuture Oncolhttps://pubmed.ncbi.nlm.nih.gov/41132084/
2025WJOG13520LREBORNThoracicDurvalumab plus irinotecan +cisplatin for untreated extensive-stage small cell lung cancer: REBORN, phase II study (WJOG13520L)Motoko TachiharaLung Cancerhttps://pubmed.ncbi.nlm.nih.gov/40602202/
2025WJOG13420GRAM-NECGIRamucirumab-containing chemotherapy for patients with gastrointestinal neuroendocrine carcinoma refractory/intolerant to platinum-based chemotherapy: a multicenter observational retrospective study (WJOG13420G)Yuki MatsubaraInt J Cancerhttps://pubmed.ncbi.nlm.nih.gov/40699213/
2025WJOG13320GNO LIMITGIPhase II Study (NO LIMIT, WJOG13320G) of First-Line Nivolumab Plus Low-Dose Ipilimumab for Microsatellite Instability–High Advanced Gastric or Esophagogastric Junction CancerHisato KawakamiJ Clin Oncolhttps://pubmed.ncbi.nlm.nih.gov/40378356/
2025WJOG12119LSQUATThoracicNeoadjuvant Concurrent Chemo-immuno-radiation Therapy Followed by Surgery and Adjuvant Immunotherapy for Resectable Stage III N2 Non-Small Cell Lung Cancer: Primary Results from SQUAT trial (WJOG 12119L)Akira HamadaJ Thorac Oncolhttps://pubmed.ncbi.nlm.nih.gov/40216327/
2025WJOG12019LThoracicIntensity-Modulated Radiotherapy for Locally Advanced Lung Cancer in the Immunotherapy Era: A Prospective Study WJOG12019LHideyuki HaradaJTO Clin Res Rephttps://pubmed.ncbi.nlm.nih.gov/40336674/
2025WJOG11218LTRThoracicSerum VEGF-A as a biomarker for the addition of bevacizumab to chemoimmunotherapy in metastatic NSCLCKentaro TanakaNat Communhttps://pubmed.ncbi.nlm.nih.gov/40121197/
2025WJOG10617GP-SELECTGISolvent-based or nab-paclitaxel plus ramucirumab for pretreated gastric cancer with peritoneal dissemination and prespecified biomarker analysis (P-SELECT/WJOG10617G): a randomised phase 2 trial in JapanKenro HirataEClinicalMedicinehttps://pubmed.ncbi.nlm.nih.gov/41660367/
2025WJOG10417GTRGIIL33-ST2 axis is a predictive biomarker for anti-PD1 therapeutic efficacy in advanced gastric cancerChie Kudo-SaitoJ Transl Medhttps://pubmed.ncbi.nlm.nih.gov/41107859/
2025WJOG10417GTRGIPeripheral SNCA+ cells as a poor prognostic factor for nivolumab therapy in advanced gastric cancerChie Kudo-SaitoDiscov Oncolhttps://pubmed.ncbi.nlm.nih.gov/41123746/
2025WJOG10417GTRGIThe FSTL1-DIP2A axis is a distinctive biomarker to predict anti-PD1 therapeutic efficacy in advanced gastric cancerChie Kudo-SaitoCancer Immunol Immunotherhttps://pubmed.ncbi.nlm.nih.gov/41251805/
2025WJOG10317LEMERALDThoracicPhase III study of ramucirumab plus docetaxel versus atezolizumab for previously treated PD-L1 low or negative advanced non-small-cell lung cancer: WJOG10317L studyYoshitaka ZenkeLung Cancerhttps://pubmed.ncbi.nlm.nih.gov/40602204/
2025JCOG1404/WJOG8214LA1ThoracicBiological impact of chemotherapy during treatment with EGFR tyrosine kinase inhibitors for non-small cell lung cancer positive for EGFR activating mutationsEiji IwamaLung Cancerhttps://pubmed.ncbi.nlm.nih.gov/40974872/
2024WJOG9717LThoracicFinal analysis data and exploratory biomarker analysis of a randomized phase II study of osimertinib plus bevacizumab versus osimertinib monotherapy for untreated patients with non-squamous non-small-cell lung cancer harboring EGFRmutations: the WJOG9717L studyHirotsugu KenmotsuJTO Clin Res Rephttps://pubmed.ncbi.nlm.nih.gov/39399795/
2024WJOG6410LTRThoracicNOTCH1 and CREBBP co-mutations negatively affect the benefit of adjuvant therapy in completely resected EGFR-mutated NSCLC: translational research of phase III IMPACT studySatoshi IkedaMol Oncolhttps://pubmed.ncbi.nlm.nih.gov/37864465/
2024WJOG5810GGIA phase 2 study of adjuvant chemotherapy with 5-fluorouracil/leucovorin and oxaliplatin after lung metastasectomy for colorectal cancer (WJOG5810G)Nozomu MachidaCancerhttps://pubmed.ncbi.nlm.nih.gov/40130723/
2024WJOG16923LThoracicA Multi-Institutional, Randomized, Phase III Trial Comparing Anatomical Segmentectomy and Lobectomy for Clinical Stage IA3 Pure-Solid Non-Small-Cell Lung Cancer: West Japan Oncology Group Study WJOG16923L (STEP UP Trial)Atsushi KamigaichiClin Lung Cancerhttps://pubmed.ncbi.nlm.nih.gov/38360496/
2024WJOG16422LJIMPACTThoracicLongitudinal recurrence risk of adjuvant cytotoxic chemotherapy and gefitnib in resected lung cancer: A combined analysis of phase III studiesHiroaki AkamatsuLung Cancerhttps://pubmed.ncbi.nlm.nih.gov/39938189/
2024WJOG14320BERICABreastA randomized, double-blind, placebo-controlled phase II study of olanzapine-based prophylactic antiemetic therapy for delayed and persistent nausea and vomiting in patients with HER2-positive or HER2-low breast cancer treated with trastuzumab deruxtecan: ERICA study (WJOG14320B)Hitomi SakaiAnn Oncolhttps://pubmed.ncbi.nlm.nih.gov/39284382/
2024WJOG13320GPSGIPrevalence and clinicopathological features of microsatellite instability-high metastatic or recurrent gastric and esophagogastric junction cancer: WJOG13320GPSAzusa KomoriGastric Cancerhttps://pubmed.ncbi.nlm.nih.gov/39738793/
2024WJOG12219LTRThoracicThe Tumor Immune Microenvironment Is Associated With Recurrence in Early-Stage Lung AdenocarcinomaHiroaki KanemuraJTO Clin Res Rephttps://pubmed.ncbi.nlm.nih.gov/38651033/
2024WJOG11919LABRAIDThoracicProspective observational study to explore genes and proteins predicting efficacy and safety of brigatinib for ALK-gene rearranged non-small-cell lung cancer: study protocol for ABRAID study (WJOG11919L)Yuichi OzawaTher Adv Med Oncolhttps://pubmed.ncbi.nlm.nih.gov/38282663/
2024WJOG11018GGIA Phase II Study of FOLFIRI Plus Ziv-Aflibercept After Trifluridine/Tipiracil Plus Bevacizumab in Patients with Metastatic Colorectal Cancer: WJOG 11018GToshihiko MatsumotoTarget Oncolhttps://pubmed.ncbi.nlm.nih.gov/38427280/
2024WJOG10417GTRGIMyeloid subsets impede the efficacy of anti-PD1 therapy in patients with advanced gastric cancer (WJOG10417GTR study)Hirokazu ShojiiJ Immunother Cancerhttps://pubmed.ncbi.nlm.nih.gov/39489543/
2024JCOG1404/WJOG8214LAGAINThoracicRandomized Phase III Study of EGFR Tyrosine Kinase Inhibitor and Intercalated Platinum-doublet Chemotherapy for Non-small Cell Lung Cancer Harboring EGFR MutationShintaro KandaClin Cancer Reshttps://pubmed.ncbi.nlm.nih.gov/40162917/
2023WJOGG11619LDOLPHINThoracicDurvalumab Plus Concurrent Radiotherapy for Treatment of Locally Advanced Non–Small Cell Lung Cancer. The DOLPHIN Phase 2 Nonrandomized Controlled Trial.Motko TachiharaJAMA Oncolhttps://pubmed.ncbi.nlm.nih.gov/37676681/
2023WJOG9616LThoracicNivolumab Retreatment in Non–Small Cell Lung Cancer Patients Who Responded to Prior Immune Checkpoint Inhibitors and Had ICI-Free Intervals (WJOG9616L)Hiroaki AkamatsuClin Cancer Reshttps://pubmed.ncbi.nlm.nih.gov/35762926/
2023WJOG9416LDRAGONThoracicDocetaxel Plus Ramucirumab With Primary Prophylactic Pegylated Granulocyte-Colony Stimulating Factor Support for Elderly Patients With Advanced NSCLC: A Multicenter Prospective Single Arm Phase 2 Trial: DRAGON Study (WJOG9416L)Motoko TachiharaJTO Clin Res Rephttps://pubmed.ncbi.nlm.nih.gov/37822699/
2023WJOG8916GGIA multicenter phase II trial of trifluridine/tipiracil in combination with cetuximab rechallenge in patients with RAS wild-type metastatic colorectal cancer refractory to prior anti-EGFR antibodies: the WJOG8916G trialNaoki IzawaTarget Oncolhttps://pubmed.ncbi.nlm.nih.gov/37148491/
2023WJOG5108LFSThoracicOverall survival analysis of patients enrolled in a randomized phase III trial comparing gefitinib and erlotinib for previously treated advanced lung adenocarcinoma (WJOG5108LFS)Nobuyuki KatakamiInt J Clin Oncolhttps://pubmed.ncbi.nlm.nih.gov/36414827/
2023WJOG15822GRETRIEVEGIRandomised phase II trial of trifluridine/tipiracil (FTD/TPI) plus ramucirumab (RAM)versus trifluridine/tipiracil for previously treated patients with advanced gastricor esophagogastric junction adenocarcinoma (RETRIEVE study, WJOG15822G)Naoki TakahashiBMC Cancerhttps://pubmed.ncbi.nlm.nih.gov/37543568/
2023WJOG15421LREVEALThoracicBiomarker Testing in Patients With Unresectable Advanced or Recurrent Non–Small Cell Lung CancerTomohiro SakamotoJAMA Netw Openhttps://pubmed.ncbi.nlm.nih.gov/38100106/
2023WJOG14720LB-DASHThoracicRandomized, open-label phase II study of brigatinib and carboplatin plus pemetrexed and brigatinib alone for chemotherapy-naive patients with ALK-rearranged non-squamous non-small cell lung cancer: treatment rationale and protocol design of the B-DASH study (WJOG 14720 L)Kazushige WakudaBMC Cancerhttps://pubmed.ncbi.nlm.nih.gov/37749521/
2023WJOG14520GGITrifluridine/Tipiracil Plus Bevacizumab for Vulnerable Patients With Pretreated Metastatic Colorectal Cancer: A Retrospective Study (WJOG14520G)Yosuke KitoOncologisthttps://pubmed.ncbi.nlm.nih.gov/37950903/
2023WJOG14320BERICABreastMulticentre, randomised, double-blind, placebo-controlled phase II study of prophylactic olanzapine for patients with metastatic breast cancer receiving T-DXd treatment: protocol for the ERICA study (WJOG14320B)Hitomi SakaiBMJ Openhttps://pubmed.ncbi.nlm.nih.gov/37012013/
2023WJOG13119LThoracicSignificance of micro-EGFR T790M mutations on EGFR-tyrosine kinase inhibitor efficacy in non-small cell lung cancerTakeshi MasudaSci Rephttps://pubmed.ncbi.nlm.nih.gov/37957228/
2023WJOG12319LTRThoracicLack of Association of Plasma Levels of Soluble Programmed Cell Death Protein 1, Programmed Death-Ligand 1, and CTLA-4 With Survival for Stage II to IIIA NSCLC After Complete Resection and Adjuvant ChemotherapyJunko TanizakiJTO Clin Res Rephttps://pubmed.ncbi.nlm.nih.gov/38029041/
2023WJOG11518LSUBMARINEThoracicTumor Microenvironment Landscape of NSCLC Reveals Resistance Mechanisms for Programmed Death-Ligand 1 Blockade After Chemoradiotherapy: A Multicenter Prospective Biomarker Study (WJOG11518L:SUBMARINE)Koji HarataniJ Thorac Oncolhttps://pubmed.ncbi.nlm.nih.gov/37364849/
2023WJOG11518LSUBMARINEThoracicAssociation of immune-related adverse events with durvalumab efficacy after chemoradiotherapy in patients with unresectable Stage III non-small cell lung cancerKoji HarataniBr J Cancerhttps://pubmed.ncbi.nlm.nih.gov/38519705/
2023WJOG11418BNEWFLAMEBreastEfficacy, safety, and biomarker analysis of nivolumab in combination with abemaciclib plus endocrine therapy in patients with HR-positive HER2-negative metastatic breast cancer: a phase II study (WJOG11418B NEWFLAME trial)Jun MasudaJ Immunother Cancerhttps://pubmed.ncbi.nlm.nih.gov/37709297/
2023WJOG11318BMERMAIDBreastEfficacy of probiotics and trimebutine maleate for abemaciclib-induced diarrhea: A randomized, open-label phase II trial (MERMAID, WJOG11318B)Hiroko MasudaBreasthttps://pubmed.ncbi.nlm.nih.gov/37459790/
2023WJOG11218LAPPLEThoracicAtezolizumab and Platinum Plus Pemetrexed With or Without Bevacizumab for Metastatic Nonsquamous Non-Small Cell Lung Cancer: A Phase 3 Randomized Clinical TrialYoshimasa ShiraishiJAMA Oncolhttps://pubmed.ncbi.nlm.nih.gov/38127362/
2023WJOG10818L TRThoracicAlternating Therapy With Osimertinib and Afatinib Blockades EGFR Secondary Mutation in EGFR-Mutant Lung Cancer: A Single-Arm Phase II TrialKimio YonesakaClin Lung Cancerhttps://pubmed.ncbi.nlm.nih.gov/37344331/
2023LOGIK1603/WJOG9116LOCEANThoracicA Phase 2 Single-Arm Study of Osimertinib for Radiotherapy-Naive Central Nervous System Metastasis NSCLC: Results for the First-Line Cohort of the OCEAN Study (LOGIK 1603/WJOG 9116L)Kazushige WakudaJTO Clin Res Rephttps://pubmed.ncbi.nlm.nih.gov/38046380/
2023JCOG0802/WJOG4607LThoracicSegmentectomy versus lobectomy in small-sized peripheral non-small-cell lung cancer (JCOG0802/WJOG4607L): a multicentre, open-label, phase 3, randomised, controlled, non-inferiority trialHisashi SajiLancethttps://pubmed.ncbi.nlm.nih.gov/35461558/
2022WJOG9917BNEWBEATBreastSafety and efficacy of nivolumab plus bevacizumab, paclitaxel for HER2-negative metastatic breast cancer: Primary results and biomarker data from a phase 2 trial (WJOG9917B)Yukinori OzakiEur J Cancerhttps://pubmed.ncbi.nlm.nih.gov/35728379/
2022WJOG7612GTRGIA phase II study to explore iomarkers for the use of mFOLFOX6/XELOX plus bevacizumab as a first-line chemotherapy in atients with metastatic colorectal cancer (WJOG7612GTR)Wataru OkamotoESMO Openhttps://pubmed.ncbi.nlm.nih.gov/36502778/
2022WJOG6410LIMPACTThoracicRandomized Phase III Study of Gefitinib Versus Cisplatin Plus Vinorelbine for Patients With Resected Stage II-IIIA Non-Small-Cell Lung Cancer With EGFR Mutation (IMPACT)Hirohito TadaJ Clin Oncolhttps://pubmed.ncbi.nlm.nih.gov/34726958/
2022WJOG13219GBRACELETGIThe Efficacy and Safety of FOLFOXIRI or Doublet plus anti-VEGF therapy in Previously Untreated BRAFV600E Mutant Metastatic Colorectal Cancer: A Multi-institutional Registry-based Study (BRACELET Study)Keitaro ShimozakiClin Colorectal Cancerhttps://pubmed.ncbi.nlm.nih.gov/36117091/
2022WJOG10818LALTThoracicAlternating Therapy with Osimertinib and Afatinib forTreatment-Naive Patients with EGFR-Mutated Advanced Non–Small Cell Lung Cancer: A Single-Group, Open-Label Phase 2 Trial (WJOG10818L)Hidetoshi HayashiLung Cancerhttps://pubmed.ncbi.nlm.nih.gov/35477147/
2022WJOG10718L@Be StudyThoracicPhase II study of atezolizumab with bevacizumab for non-squamous non-small cell lung cancer with high PD-L1 expression (@Be Study)Takashi SetoJ Immunother Cancerhttps://pubmed.ncbi.nlm.nih.gov/35105689/
2022J-SONICThoracicNintedanib plus chemotherapy for nonsmall cell lung cancer with idiopathic pulmonary fibrosis: a randomised phase 3 trialKohei OtsuboEur Respir Jhttps://pubmed.ncbi.nlm.nih.gov/35361630/
2022JCOG0804/ WJOG4507LThoracicA single-arm study of sublobar resection for ground-glass opacity dominant peripheral lung cancerKenji SuzukiInteract Cardiovasc Thorac Surghttps://pubmed.ncbi.nlm.nih.gov/25987718/
2021WJOG9116LOCEANThoracicA Phase II Study of Osimertinib for Radiotherapy-Naive Central Nervous System Metastasis From NSCLC: Results for the T790M Cohort of the OCEAN Study (LOGIK1603/WJOG9116L)Hiroyuki YamaguchiJ Thorac Oncolhttps://pubmed.ncbi.nlm.nih.gov/34419684/
2021WJOG8815L/LPS/LFSThoracicPredicting osimertinib‐treatment outcomes through EGFR mutant‐fraction monitoring in the circulating tumor DNA of EGFR T790M‐positive patients with non‐small cell lung cancer (WJOG8815L)Kazuko SakaiMol Oncolhttps://pubmed.ncbi.nlm.nih.gov/33131198/
2021WJOG8715LThoracicEfficacy of Osimertinib Plus Bevacizumab vs Osimertinib in Patients With EGFR T790M–Mutated Non–Small Cell Lung Cancer Previously Treated With Epidermal Growth Factor Receptor–Tyrosine Kinase Inhibitor: West Japan Oncology Group 8715L Phase 2 Randomized Clinical TrialHiroaki AkamatsuJAMA Oncolhttps://pubmed.ncbi.nlm.nih.gov/33410885/
2021WJOG8515LThoracicA Randomized Phase 2 Study Comparing Nivolumab with Carboplatin-Pemetrexed for EGFR-Mutated NSCLC with Resistance to EGFR Tyrosine Kinase Inhibitors (WJOG8515L)Hidetoshi HayashiClin Cancer Reshttps://pubmed.ncbi.nlm.nih.gov/34921023/
2021WJOG7312GGIClinical implications of using both fluoropyrimidine and paclitaxel in patients with severe peritoneal metastasis of gastric cancer: A post-hoc study of JCOG1108/WJOG7312GHiroyuki AraiCancer Medhttps://pubmed.ncbi.nlm.nih.gov/34655175/
2021WJOG6911LThoracicGefitinib With Concurrent Thoracic Radiotherapy in Unresectable Locally Advanced NSCLC With EGFR Mutation; West Japan Oncology Group 6911LHiroaki AkamatsuJ Thorac Oncolhttps://pubmed.ncbi.nlm.nih.gov/34116229/
2021WJOG13320GNO LIMITGIAn Investigator-Initiated Phase 2 Study of Nivolumab Plus Low-Dose Ipilimumab as First-Line Therapy for Microsatellite Instability—High Advanced Gastric or Esophagogastric Junction Cancer (NO LIMIT, WJOG13320G/CA209-7W7)Hisato KawakamiCancershttps://pubmed.ncbi.nlm.nih.gov/33671871/
2021WJOG13019LThoracicReal-world data on NGS using the Oncomine DxTT for detecting genetic alterations in non-small cell lung cancer: WJOG13019LShinya SakataCancer Scihttps://pubmed.ncbi.nlm.nih.gov/34704312/
2021WJOG12819LThoracicA Phase II Study to Assess the Efficacy of Osimertinib in Patients With EGFR Mutation-positive NSCLC Who Developed Isolated CNS Progression (T790M-negative or Unknown) During First- or Second-generation EGFR-TKI or Systemic Disease Progression (T790M-negative) After Treatment With First- or Second-generation EGFR-TKI and Platinum-based Chemotherapy (WJOG12819L)Masayuki TakedaClin Lung Cancerhttps://pubmed.ncbi.nlm.nih.gov/33612406/
2021WJOG12519BBreastClinical benefit of treatment after trastuzumab-emtansine for HER2-positive metastatic breast cancer: A real-world multi-centre cohort study in Japan (WJOG12519B)Takamichi YokoeBreast Cancerhttps://pubmed.ncbi.nlm.nih.gov/33389616/
2021WJOG12119LSQUAThoracicPhase II Study of Neoadjuvant Concurrent Chemo-immuno-radiation Therapy Followed by Surgery and Adjuvant Immunotherapy for Resectable Stage IIIA-B (Discrete N2) Non–small-cell Lung Cancer: SQUAT trial (WJOG 12119L)Akira HamadaClin Lung Cancerhttps://pubmed.ncbi.nlm.nih.gov/34034990/
2021WJOG11619LDOLPHINThoracicRationale and Design for a Multicenter, Phase II Study of Durvalumab Plus Concurrent Radiation Therapy in Locally Advanced Non-Small Cell Lung Cancer: The DOLPHIN Study (WJOG11619L)Motoko TachiharaCancer Manag Reshttps://pubmed.ncbi.nlm.nih.gov/34934361/
2021WJOG11118LTRAP OLIGOThoracicPhase II study of multidisciplinary therapy combined with pembrolizumab for patients with synchronous oligometastatic nonsmall cell lung cancer TRAP OLIGO study (WJOG11118L)Taichi MiyawakiBMC Cancerhttps://pubmed.ncbi.nlm.nih.gov/34663250/
2021WJOG0105LFSThoracicEffect of Second-generation vs Third-generation Chemotherapy Regimens With Thoracic Radiotherapy on Unresectable Stage III Non–Small-Cell Lung Cancer: 10-Year Follow-up of a WJTOG0105 Phase 3 Randomized Clinical TrialYoshitaka ZenkeJAMA Oncolhttps://pubmed.ncbi.nlm.nih.gov/33734289/
2020WJOG9516LThoracicSequential therapy of crizotinib followed by alectinib for non-small cell lung cancer harbouring anaplastic lymphoma kinase rearrangement (WJOG9516L): A multicenter retrospective cohort studyKentaro ItoEur J Cancerhttps://pubmed.ncbi.nlm.nih.gov/33486442/
2020WJOG8815L/LPSThoracicPlasma screening for the T790M mutation of EGFR and phase 2 study of osimertinib efficacy in plasma T790M–positive non–small cell lung cancer: West Japan Oncology Group 8815L/LPS studyTakayuki TakahamaCancerhttps://pubmed.ncbi.nlm.nih.gov/32022929/
2020WJOG7813L/JCOG1210ThoracicComparison of Carboplatin Plus Pemetrexed Followed by Maintenance Pemetrexed With Docetaxel Monotherapy in Elderly Patients With Advanced Nonsquamous Non–Small Cell Lung Cancer A Phase 3 Randomized Clinical TrialIsamu OkamotoJAMA Oncolhttps://pubmed.ncbi.nlm.nih.gov/32163097/
2020WJOG7512LThoracicA Randomized Phase III Study of Maintenance Therapy with S-1 Plus Best Supportive Care Versus Best Supportive Care After Induction Therapy with Carboplatin Plus S-1 for Advanced or Relapsed Squamous Cell Carcinoma of the Lung (WJOG7512L)Kaoru TanakaCancerhttps://pubmed.ncbi.nlm.nih.gov/32484914/
2020WJOG7312GGIRandomized phase II/III study of 5-fluorouracil/l-leucovorin versus 5-fluorouracil/l-leucovorin plus paclitaxel administered to patients with severe peritoneal metastases of gastric cancer (JCOG1108/WJOG7312G)Takako Eguchi NakajimaGastric Cancerhttps://pubmed.ncbi.nlm.nih.gov/32036492/
2020WJOG7112GT-ACTGIRandomized, Phase II Study of Trastuzumab Beyond Progression in Patients With HER2-Positive Advanced Gastric or Gastroesophageal Junction Cancer: WJOG7112G (T-ACT Study)Akitaka MakiyamaJ Clin Oncolhttps://pubmed.ncbi.nlm.nih.gov/32208960/
2020WJOG6811BBreastA double‐blind, randomized, multicenter phase 3 study of palonosetron vs granisetron combined with dexamethasone and fosaprepitant to prevent chemotherapy‐induced nausea and vomiting in patients with breast cancer receiving anthracycline and cyclophosphamideKoji MatsumotoCancer Medicinehttps://pubmed.ncbi.nlm.nih.gov/32168551/
2020WJOG6510GTRGIBiomarker Analysis in A Randomized Phase 2 Study of Panitumumab Versus Cetuximab in Colorectal Cancer (WJOG6510GTR)Hiroya TaniguchiJ Cancer Sci Clin Therhttps://www.fortunejournals.com/articles/biomarker-analysis-in-a-randomized-phase-2-study-of-panitumumab-versus-cetuximab-in-colorectal-cancer-wjog6510gtr.html
2020WJOG6510GGIRandomised phase II study of panitumumab plus irinotecan versus cetuximab plus irinotecan in patients with KRAS wild-type metastatic colorectal cancer refractory to fluoropyrimidine, irinotecan and oxaliplatin (WJOG 6510G)Daisuke SakaiEur J Cancerhttps://pubmed.ncbi.nlm.nih.gov/32526634/
2020WJOG6210GSS2GIEarly Tumor Shrinkage and Depth of Response in the Second-Line Treatment for KRAS exon2 Wild-Type Metastatic Colorectal Cancer: An Exploratory Analysis of the Randomized Phase 2 Trial Comparing Panitumumab and Bevacizumab in Combination with FOLFIRI (WJOG6210G)Naoki IzawaTarget Oncolhttps://pubmed.ncbi.nlm.nih.gov/32960408/
2020WJOG5610LCOMPASSThoracicRandomized Phase III Study of Continuation Maintenance Bevacizumab With or Without Pemetrexed in Advanced Nonsquamous Non-Small-Cell Lung Cancer: COMPASS (WJOG5610L)Takashi SetoJ Clin Oncolhttps://pubmed.ncbi.nlm.nih.gov/31880966/
2020WJOG4407GSS2GITime-dependent discrepancies between physician-assessed and patient-reported oxaliplatin-induced peripheral neuropathy in patients with metastatic colorectal cancer who received mFOLFOX6 plus bevacizumab: a post-hoc analysis (WJOG4407GSS2)Yuji MiuraSupport Care Cancerhttps://pubmed.ncbi.nlm.nih.gov/33200233/
2020WJOG4407GSSGIMorphologic response to chemotherapy containing bevacizumab in patinets with colorectal liver metastases. A post hoc analysis of the WJOG4407G phase III studyAyumu HosokawaMedicinehttps://pubmed.ncbi.nlm.nih.gov/32899071/
2020WJOG11719LADJUSTThoracicA phase II study of cisplatin plus vinorelbine combined with atezolizumab as adjuvant therapy for completely resected non-small-cell lung cancer with EGFR mutation (West Japan Oncology Group 11719L/ADJUST study)Ryota ShibakiTher Adv Med Oncolhttps://pubmed.ncbi.nlm.nih.gov/33613698/
2020WJOG112181LAPPLEThoracicTreatment Rationale and Design for APPLE (WJOG11218L): A Multicenter, Open-Label, Randomized Phase 3 Study of Atezolizumab and Platinum/Pemetrexed With or Without Bevacizumab for Patients With Advanced Nonsquamous Non–Small-Cell Lung CancerYoshimasa ShiraishiClin Lung Cancerhttps://pubmed.ncbi.nlm.nih.gov/32381420/
2020WJOG10617GP-SELECTGIWeekly paclitaxel plus ramucirumab versus weekly nab-paclitaxel plus ramucirumab for unresectable advanced or recurrent gastric cancer with peritoneal dissemination refractory to first-line therapy-the P-SELECT trial (WJOG10617G)-a randomised phase II trial by the West Japan Oncology GroupKenro HirataBMC Cancerhttps://pubmed.ncbi.nlm.nih.gov/32532230/
2020WJOG10517GGIWJOG10517G: a multicenter Phase II study of mFOLFOX6 in gastric cancer patients with severe peritoneal metastasesToshiki MasuishiFuture Oncolhttps://pubmed.ncbi.nlm.nih.gov/32466683/
2020WJOG10217LThoracicPropensity Score-Weighted Analysis of Chemotherapy After PD-1 Inhibitors Versus Chemotherapy Alone in Patients With Non-Small Cell Lung Cancer (WJOG10217L)Ryoji KatoJ Immunother Cancerhttps://pubmed.ncbi.nlm.nih.gov/32066647/
2020WJOG 9116L/LOGIK 1603OCEANThoracicA phase II study of Osimertinib for patients with radiotherapy-naïve CNS metastasis of non-small cell lung cancer: treatment rationale and protocol design of the OCEAN study (LOGIK 1603/WJOG 9116L)Kazushige WakudaBMC Cancerhttps://pubmed.ncbi.nlm.nih.gov/32357848/
2020ASPECCT/WJOG6510GGIEfficacy of Panitumumab and Cetuximab in Patients with Colorectal Cancer Previously Treated with Bevacizumab; a Combined Analysis of Individual Patient Data from ASPECCT and WJOG6510GHiroya TaniguchiCancershttps://pubmed.ncbi.nlm.nih.gov/32605298/
2019WJTOG3405ThoracicFinal overall survival results of WJTOG3405, a randomized phase III trial comparing gefitinib versus cisplatin with docetaxel as the first-line treatment for patients with stage IIIB/IV or postoperative recurrent EGFR mutation-positive non-small-cell lung cancerHiroshige YoshiokaAnn Oncolhttps://pubmed.ncbi.nlm.nih.gov/31553438/
2019WJOG8715LThoracicPhase I/II Study of Osimertinib With Bevacizumab in EGFR-mutated, T790M-positive Patients With Progressed EGFR-TKIs: West Japan Oncology Group 8715L (WJOG8715L)Hiroaki AkamatsuClin Lung Cancerhttps://pubmed.ncbi.nlm.nih.gov/31085043/
2019WJOG8114LTRThoracicClinical significance of monitoring EGFR mutation in plasma using multiplexed digital PCR in EGFR mutated patients treated with afatinib (West Japan Oncology Group 8114LTR study)Hiroaki AkamatsuLung Cancerhttps://pubmed.ncbi.nlm.nih.gov/31027689/
2019WJOG6911LThoracicA phase II study of gefitinib with concurrent thoracic radiotherapy in patients with unresectable, stage III Non-Small Cell Lung Cancer harboring EGFR mutations (WJOG6911L)Hiroaki AkamatsuClin Lung Cancerhttps://pubmed.ncbi.nlm.nih.gov/30266586/
2019WJOG4708LThoracicPhase I/II study of intermitted erlotinib in combination with docetaxel in patients with recurrent non-small cell lung cancer (WJOG4708L)Tatsuo KimuraJpn J Clin Oncolhttps://pubmed.ncbi.nlm.nih.gov/31242302/
2019WJOG4607LThoracicComparison of pulmonary segmentectomy and lobectomy: Safety results of a randomized trialKenji SuzukiJ Thorac Cardiovasc Surghttps://pubmed.ncbi.nlm.nih.gov/31078312/
2018WJOG6110BELTOPBreastA randomized phase II trial of trastuzumab plus capecitabine versus lapatinib plus capecitabine in patients with HER2-positive metastatic breast cancer previously treated with trastuzumab and taxanes: WJOG6110B/ELTOPToshimi TakanoBreasthttps://pubmed.ncbi.nlm.nih.gov/29698927/
2018WJOG5308LThoracicInduction Chemo-radiation (50Gy) Followed by Surgery for Stage IIIA-N2 Non-small Cell Lung CancerFumihiro TanakaAnn Thorac Surg
https://pubmed.ncbi.nlm.nih.gov/29890150/
2018WJOG5008LThoracicA randomized phase II trial of S-1 plus cisplatin versus vinorelbine plus cisplatin with concurrent thoracic radiotherapy for unresectable, locally advanced non-small cell lung cancer: WJOG5008LTomonari SasakiBr J Cancerhttps://pubmed.ncbi.nlm.nih.gov/30206369/
2017WJOG7212GGIFive-weekly S-1 plus cisplatin with trastuzumab in HER2-positive gastric cancer: a phase II trial and biomarker study (WJOG7212G)Yuji MiuraGastric Cancerhttps://pubmed.ncbi.nlm.nih.gov/28497176/
2017PCIThoracicProphylactic cranial irradiation versus observation in patients with extensive-disease small-cell lung cancer: a multicentre, randomised, open-label, phase 3 trialToshiaki TakahashiLancet Oncolhttps://pubmed.ncbi.nlm.nih.gov/28343976/
2017J-SONICThoracicTreatment Rationale and Design for J-SONIC: A Randomized Study of Carboplatin Plus Nab-paclitaxel With or Without Nintedanib for Advanced NoneSmall-cell Lung Cancer With Idiopathic Pulmonary FibrosisKohei OtsuboClin Lung Cancerhttps://pubmed.ncbi.nlm.nih.gov/28687482/
2016WJOG8014LTRThoracicDetection of the T790M mutation of EGFR in plasma of advanced non 13;small cell lung cancer patients with acquired resistance to tyrosine kinase inhibitors (West Japan oncology group 8014LTR study)Takayuki TakahamaOncotargethttps://pubmed.ncbi.nlm.nih.gov/27542267/
2016WJOG6711LPEOPLEThoracicA phase II trial evaluating the efficacy and safety of perioperative pirfenidone for prevention of acute exacerbation of idiopathic pulmonary fibrosis in lung cancer patients undergoing pulmonary resection: West Japan Oncology Group 6711L (PEOPLE Study)Takekazu IwataRespir Reshttps://pubmed.ncbi.nlm.nih.gov/27450274/
2016WJOG6210GGIRandomized study of FOLFIRI plus either panitumumab or evacizumab for wild-type KRAS colorectal cancer-WJOG 6210GKohei ShitaraCancer Scihttps://pubmed.ncbi.nlm.nih.gov/27712015/
2016WJOG5910LThoracicBevacizumab Beyond Disease Progression After First-Line Treatment With Bevacizumab Plus Chemotherapy in Advanced Nonsquamous Non–Small Cell Lung Cancer (West Japan Oncology Group 5910L): An Open-Label, Randomized, Phase2 TrialMasayuki TakedaCancerhttps://pubmed.ncbi.nlm.nih.gov/26828788/
2016WJOG5108LThoracicRandomized Phase III Study Comparing Gefitinib with Erlotinib in Patients with Previously Treated Advanced Lung Adenocarcinoma: WJOG 5108LYoshiko UrataJ Clin Oncolhttps://pubmed.ncbi.nlm.nih.gov/27022112/
2016WJOG4407GGIRandomized phase III study of bevacizumab plus FOLFIRI and bevacizumab plus mFOLFOX6 as first-line treatment for patients with metastatic colorectal cancer (WJOG4407G)Kentaro YamazakiAnn Oncolhttps://pubmed.ncbi.nlm.nih.gov/27177863/
2015WJOG5208LThoracicNedaplatin plus docetaxel versus cipliatin plus docetaxel for advanced or relapsed squamous cell carcinoma of the lungTakehito ShukuyaLancet Oncolhttps://pubmed.ncbi.nlm.nih.gov/26522337/
2015WJOG4207LThoracicA multicenter phase II study of carboplatin and paclitaxel for advanced thymic carcinoma: WJOG4207 LFumihiko HiraiAnn Oncolhttps://pubmed.ncbi.nlm.nih.gov/25403584/
2015WJOG4107ThoracicRandomized Phase II Study of Adjuvant Chemotherapy with Long-term S-1 versus Cisplatin+S-1 in Completely Resected Stage II–IIIA Non–Small Cell Lung CancerYasuo IwamotoClin Cancer Reshttps://pubmed.ncbi.nlm.nih.gov/26253869/
2015JCOG0803/WJOG4307LThoracicRandomized Phase III Trial Comparing Weekly Docetaxel Plus Cisplatin Versus Docetaxel Monotherapy Every 3 Weeks in Elderly Patients With Advanced Non–Small-Cell Lung Cancer: The Intergroup Trial JCOG0803/WJOG4307LTetsuya AbeJ Clin Oncolhttps://pubmed.ncbi.nlm.nih.gov/25584004/
2014WJTOG3806ThoracicA Phase II Study of Zoledronic Acid Combined with Docetaxel for Non–small-cell Lung Cancer: West Japan Oncology GroupHaruyasu MurakamiCancer Scihttps://pubmed.ncbi.nlm.nih.gov/24837137/
2014WJTOG0302ThoracicA phase I/II Trial of Irinotecan Plus Amrubicin Supported with G-CSF for Extended Small-cell Lung CancerTaishi HaradaJpn J Clin Oncolhttps://pubmed.ncbi.nlm.nih.gov/24379211/
2014WJOG6611LTRThoracicMultiplex genomic profiling of non–small cell lung cancers from the LETS phase III trial of first-line S-1/carboplatin versus paclitaxel/carboplatin: results of a West Japan Oncology Group studyIsamu OkamotoOncotargethttps://pubmed.ncbi.nlm.nih.gov/24810493/
2013WJTOG3605LETSThoracicEfficacy and safety analysis according to histology for S-1 in combination with carboplatin as first-line chemotherapy in patients with advanced non-small-cell lung cancer: updated results of the West Japan Oncology Group LETS studyHiroshige YoshiokaAnn Oncolhttps://pubmed.ncbi.nlm.nih.gov/23277482/
2013WJOG4007ThoracicRandomized, Open-label, Phase III Study Comparing Irinotecan With Paclitaxel in Patients With Advanced Gastric Cancer Without Severe Peritoneal Metastasis After Failure of Prior Combination Chemotherapy Using Fluoropyrimidine Plus Platinum: WJOG4007 TrialShuichi HironakaJ Clin Oncolhttps://pubmed.ncbi.nlm.nih.gov/24190112/
2013WJOG3906LThoracicHistology and Smoking Status Predict Survival of Patients with Advanced Non–Small-Cell Lung CancerResults of West Japan Oncology Group (WJOG) Study 3906LYoshihito KogureJ Thorac Oncolhttps://pubmed.ncbi.nlm.nih.gov/23575412/
2013NEJ 002/WJTOG 3405ThoracicInterstitial Lung Disease Associated with Gefitinib in Japanese Patients with EGFR-mutated Non-small-cell Lung Cancer: Combined Analysis of Two Phase III Trials (NEJ 002 and WJTOG 3405)Hiroaki AkamatsuJpn J Clin Oncolhttps://pubmed.ncbi.nlm.nih.gov/23585689/
2012WJTOG9903ThoracicA phase 3 study of induction treatment with concurrent chemorad iotherapy versus chemotherapy before surgery in patients with pathologically confirmed N2 stage IIIA nonsmall cell lung cancer (WJTOG9903)Nobuyuki KatakamiCancerhttps://pubmed.ncbi.nlm.nih.gov/22674529/
2012WJTOG3305ThoracicA phase I study of chemoradiotherapy with use of involved-field conformal radiotherapy and accelerated hyperfractionation for stage III non-small cell lung cancer: WJTOG3305Takuhito TadaInt J Radiat Oncol Biol Phys
https://pubmed.ncbi.nlm.nih.gov/22079726/
2012WJTOG3005ThoracicPhase I Results of Vinorelbine With Concurrent Radiotherapy in Elderly Patients With Unresectable, Locally Advanced Non-Small-Cell Lung Cancer: West Japan Thoracic Oncology Group (WJTOG3005-DI)Hideyuki HaradaInt J Radiat Oncol Biol Physhttps://pubmed.ncbi.nlm.nih.gov/21621337/
2012WJTOG2905ThoracicA combination phase I /II study of gemcitabine with carboplatin for previously untreated elderly non-small cell lung cancer; WJTOG 2905Takayasu KurataLung Cancerhttps://pubmed.ncbi.nlm.nih.gov/22306126/
2012WJTOG0004ThoracicRandomized Phase II Study of Carboplatin-Paclitaxel or Gemcitabine-Vinorelbine in Advanced Nonsmall Cell Lung Cancer and a Performance Status of 2. West Japan Thoracic Oncology Group 0004Hiroshi SaitoAm J Clin Oncolhttps://pubmed.ncbi.nlm.nih.gov/21293243/
2012WJOG5910LThoracicImpact of treatment with bevacizumab beyond disease progression: a randomized phase II study of docetaxel with or without bevacizumab after platinum-based chemotherapy plus bevacizumab in patients with advanced nonsquamous non–small cell lung cancer (WJOG5910L)Masayuki TakedaBMC Cancerhttps://pubmed.ncbi.nlm.nih.gov/22849580/
2011WJTOG3706ThoracicS-1 plus cisplatin with concurrent radiotherapy for locally advanced non-small cell lung cancer. A muti-institutional phase II trial (West Japan Thoracic Oncology Group 3706)Yukito IchinoseJ Thorac Oncolhttps://pubmed.ncbi.nlm.nih.gov/22052226/
2011WJTOG0402ThoracicPhase II Study of Gefitinib as a First-line Therapy in Elderly Patients with Lung Adenocarcinoma: WJTOG 0402Masahi KobayashiJpn J Clin Oncolhttps://pubmed.ncbi.nlm.nih.gov/21715363/
2010WJTOG3605ThoracicPhase III Trial Comparing Oral S-1 Plus Carboplatin With Paclitaxel Plus Carboplatin in Chemotherapy-Naïve Patients With Advanced Non–Small-Cell Lung Cancer: Results of a West Japan Oncology Group StudyIsamu OkamotoJ Clin Oncolhttps://pubmed.ncbi.nlm.nih.gov/21079147/
2010WJTOG3405ThoracicGefitinib versus cisplatin/docetaxel in patients with non-small cell lung cancer harbouring mutations of epidermal growth factor receptor (WJTOG3405): a randomized phase 3 trialTetsutya MitsudomiLancet Oncolhttps://pubmed.ncbi.nlm.nih.gov/20022809/
2010WJTOG0401ThoracicPhase II Trial of Amrubicin for Second-Line Treatment of Advanced Non-small Cell Lung Cancer: Results of the West Japan Thoracic Oncology Group Trial (WJTOG0401)Hiroyasu KanedaJ Thorac Oncolhttps://pubmed.ncbi.nlm.nih.gov/19884859/
2010WJTOG0301ThoracicPhase II Study of Sequential Triplet Chemotherapy, Irinotecan and Cisplatin Followed by Amrubicin, in Patientswith Extensive-Stage Small Cell Lung Cancer: West Japan Thoracic Oncology Group Study 0301Masashi KobayashiJ Thorac Oncolhttps://pubmed.ncbi.nlm.nih.gov/20479694/
2010WJTOG0203ThoracicRandomized phase III trial of platinum-doublet chemotherapy followed by gefitinib versus continued platinum-doublet chemotherapy in Japanese patients with advanced non-small cell lung cancer: results of a West Japan Thoracic Oncology Group trial (WJTOG0203)Koji TakedaJ Clin Oncolhttps://pubmed.ncbi.nlm.nih.gov/20038730/
2010WJTOG0105ThoracicPhase III comparative study of a second generation regimen and third generation regimens with concurrent thoracic radiotherapy in patients with unresectable stage III non-small-cell lung cancer: West Japan Oncology Group WJTOG0105Nobuyuki YamamotoJ Clin Oncolhttps://pubmed.ncbi.nlm.nih.gov/20625120/
2009WJTOG0202ThoracicA phase I study of topotecan plus carboplatin for relapsed SCLC: WJTOG trialTakayasu KurataJ Thorac Oncolhttps://pubmed.ncbi.nlm.nih.gov/19325498/
2009ThoracicCombined survival analysis of prospective clinical trials of gefitinib for non-small cell lung cancer with EGFR mutationsSatoshi MoritaClin Cancer Reshttps://pubmed.ncbi.nlm.nih.gov/19531624/
2008WJTOG3505ThoracicPhase II Study of Combination Therapy with S-1 and Irinotecan for Advanced Non-Small Cell Lung Cancer: West Japan Thoracic Oncology Group 3505Isamu OkamotoClin Cancer Reshttps://pubmed.ncbi.nlm.nih.gov/18698044/
2008WJTOG0403ThoracicMulticenter prospective phase II trial of gefitinib for advanced non-small cell lung cancer with epidermal growth factor receptor mutation: results of the West Japan Oncology Group trial (WJTOG0403)Kenji TamuraBr J Cancerhttps://pubmed.ncbi.nlm.nih.gov/18283321/
2007WJTOG0002ThoracicPhase I/II trial of sequential chemoradiotherapy using a novel hypoxic cell radiosensitizer, doranidazole (PR-350), in patients with locally advanced non-small-cell lung Cancer (WJTOG-0002)Yasumasa NishimuraInt J Radiat Oncol Biol Physhttps://pubmed.ncbi.nlm.nih.gov/17512126/
2007ThoracicPhase II study of amrubicin, 9-amino-anthracycline, in patients with advanced non-small-cell lung cancer: a West Japan Thoracic Oncology Group studyKoji TakedaInvest New Drugshttps://pubmed.ncbi.nlm.nih.gov/17351748/
2006WJTOG9904ThoracicPhase Ⅲ Study of Docetaxel Compared With Vinorelbine in Elderly Patients With Advanced Non-Small-Cell Lung Cancer: Results of the West Japan Thoracic Oncology Group Trial (WJTOG9904)Shinzoh KudohJ Clin Oncolhttps://pubmed.ncbi.nlm.nih.gov/16877734/
2006WJTOG9902ThoracicPhaseⅡStudy of Etoposide and Cisplatin With Concurrent Twice-Daily Thoracic Radiotherapy Followed by Irinotecan and Cisplatin in Patients With Limited-Disease Small-Cell Lung Cancer: West Japan Thoracic Oncology Group 9902Hiroshi SaitoJ Clin Oncolhttps://pubmed.ncbi.nlm.nih.gov/17114657/
2006WJTOG0104ThoracicRandomized phase II study of carboplatin/gemcitabine versus vinorelbine/gemcitabine in patients with advanced non-small cell lung cancer: West Japan Thoracic Oncology Group (WJTOG) 0104Nobuyuki YamamotoCancerhttps://pubmed.ncbi.nlm.nih.gov/16804877/
2006ThoracicPredictive Factors for Interstitial Lung Disease, Antitumor Response and Survival in Non-Small-Cell Lung Cancer Patients Treated With GefitinibMasahiko AndoJ Clin Oncolhttps://pubmed.ncbi.nlm.nih.gov/16735708/
2005ThoracicIrinotecan and etoposide for previously untreated extensive-disease small cell lung cancer: A phase II trial of West Japan Thoracic Oncology GroupShinzoh KudohLung Cancerhttps://pubmed.ncbi.nlm.nih.gov/16022921/
2004WJTOG9908ThoracicCombination chemotherapy of gemcitabine and vinorelbine for patients in stage IIIB-IV non-small cell lung cancer: a phase II study of the West Japan Thoracic Oncology Group (WJTOG) 9908Nobuyuki KatakamiLung Cancerhttps://pubmed.ncbi.nlm.nih.gov/14698543/
2004WJTOG9803ThoracicRandomised phase II study of docetaxel/cisplatin vs docetaxel/irinotecan in advanced non-small-cell lung cancer: a West Japan Thoracic Oncology Group Study (WJTOG9803)Nobuyuki YamamotoBr J Cancerhttps://pubmed.ncbi.nlm.nih.gov/14710212/