Welcome to the international website of WJOG!
We are constantly exploring new research opportunities.
Message from the Chairman
The West Japan Oncology Group (WJOG; the Group) was established in 2000 to conduct clinical studies on lung cancer. Since then, WJOG has added a gastrointestinal cancer group in 2007 and a breast cancer group in 2009. In 2021, the Group established a basket group to conduct clinical studies based on cross-organ biomarkers. Under the leadership of the individual group head, each group actively drafts and implements clinical studies. As of January 2026, WJOG has grown to become one of Japan's largest clinical study groups conducting 41 clinical studies with the participation of 389 facilities in Japan. Its findings have been published in prominent journals and shared with international academic societies. In recent years, the scope of the WJOG activities has broadened to include the collection of real-world data on cancer, the training of young researchers, and active cooperation with cancer patients through patient and public involvement (PPI) and other initiatives, in addition to clinical studies.
Specifically, the WJOG collects prospective real-world data on thousands of lung cancer patients, which the Group plans to make available for flexible use through activities that include joint research with corporate and other partners. With regard to cooperation with patient organizations, WJOG has been a member of the Global Lung Cancer Coalition for many years and is conducting clinical research proposed by a patient organization on the subject of EGFR-mutant lung cancer (Takeda M, et al: Lung Cancer 2023 and 2024). The three groups on lung cancer, gastrointestinal cancer, and breast cancer have established the WING, FLAG, and BLIGHT groups of young researchers, each with dozens of members, which are actively proposing clinical studies. The FLAG group also meets with the German clinical testing group AIO.
While the WJOG successively publishes the results of clinical studies through academic societies, English-language papers, and other means, most of its other activities are not widely known outside of Japan. Traditionally, research on cancer examinations and treatment consisted mainly of global joint research because of the considerable resources required. The WJOG has decided to open an English-language website to more actively promote global collaboration to let people around the world become more aware of its activities.
The WJOG appreciates your continued support.

About WJOG
WJOG is a leading multi-institutional clinical trial group in Japan.
WJOG is a certified non-profit organization (NPO) in Japan dedicated to advanced cancer treatment and clinical research. WJOG has four groups: Thoracic Oncology Group, Gastrointestinal Oncology Group, Breast Oncology Group, and Basket Trial Committee.
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Thoracic
Oncology Group -
Gastrointestinal
Oncology Group -
Breast
Oncology Group -
Basket Trial
Committee
Directors
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Chairman
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Vice Chairman
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- Nobuyuki Yamamoto
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Chairman
Wakayama Medical University Hospital
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- Narikazu Boku
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Vice Chairman
The University of Tokyo Institute of Medical Science Hospital
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- Koji Takeda
- West Japan Oncology Group
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Executive Director
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- Hirotsugu Kenmotsu
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Executive Director
Shizuoka Cancer Center
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- Kei Muro
- Aichi Cancer Center
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- Toshimi Takano
- Cancer Institute Hospital of JFCR
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- Hidetoshi Hayashi
- Kindai University Faculty of Medicine
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- Kentaro Yamazaki
- Shizuoka Cancer Center
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- Satoru Miura
- Miura Clinic
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- Naoki Ishizuka
- Kyoto University Graduate School of Medicine
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- Isamu Okamoto
- Kyushu University Hospital
WJOG by the Numbers
- Founded
in1991 - Total enrolled
patients(2000-2025)26,864 - Active
Clinical Trials41 - Participating
Institutions389 - Active
WJOG Members958
2026.02.08 update
Key Clinical Trials
We have many more clinical trials in progress, and we are constantly exploring new research opportunities.
| Study Group | Study Number | Study Type | Study Title | Clinical Trials Registry |
|---|---|---|---|---|
| Thoracic | WJOG20924L (J-OLIGO) |
Ⅲ | Phase III study of multidisciplinary therapy combined local ablative therapy with immune-checkpoint inhibitors for patients with synchronous oligometastatic NSCLC (J-OLIGO: WJOG20924L) | jRCTs041250114 |
| Gastrointestinal | WJOG19524G | Ⅱ | A Phase II Clinical Trial Evaluating the Antiemetic Effect and Safety of a Five-Drug Combination Therapy for Zolbetuximab, Including Olanzapine and Antihistamines, with or without Pre-Treatment Olanzapine (OPTIMIZE:WJOG19524G) | jRCTs041250124 |
| Breast | WJOG18123B (SAKURA) |
Ⅱ | WJOG18123B: Randomized placebo-controlled study of S-equol containing supplement for the control of aromatase inhibitor-induced musculoskeletal pain and stiffness in hands (SAKURA) | jRCTs031240754 |
| Basket | WJOG15221M (ALLBREAK) |
Ⅱ | A multicenter phase II study of brigatinib for patients with ALK fusion genes positive metastatic solid tumor (WJOG15221M/ XB99036) | jRCT2041210148 |
Our Publications
WJOG has conducted many clinical trials. For more information, please click the button below.
Collaboration Process with WJOG
For Academic and Industry Partners
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Initial Inquiry
Contact the Investigators or use the "contact us".(Submission of a research idea or collaboration proposal)
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Preliminary Discussion
Conceptual Discussion at the WJOG Advisory Meeting(Scientific rationale, feasibility, collaboration framework, and alignment with WJOG mission)
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Concept Review
Review by the WJOG Executive Board(Decision to proceed to protocol development)
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Protocol Development
Detailed Study Planning(Study design, endpoints, operational feasibility, roles and responsibilities)
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Final Approval & Study Initiation
Protocol Approval and Study Launch(Approval by the WJOG Executive Board and institutional IRB review)
All studies are conducted in compliance with ethical guidelines and ICH-GCP.
Contact
Access
1-5-7 Motomachi, Naniwa-ku, Osaka-city, Osaka 556-0016, JAPAN